基础医学与临床 ›› 2008, Vol. 28 ›› Issue (9): 998-1000.

• 短篇综述 • 上一篇    下一篇

腺相关病毒Rep78/68蛋白

刘天会 尤红   

  1. 首都医科大学附属北京友谊医院 首都医科大学附属北京友谊医院
  • 收稿日期:2007-07-16 修回日期:2007-12-11 出版日期:2008-09-25 发布日期:2008-09-25
  • 通讯作者: 尤红

Rep78/68 protein of adeno-associated virus

Tian-hui LIU, Hong YOU   

  1. Beijing Friendship Hospital, Capital Medical University Beijing Friendship Hospital, Capital Medical University
  • Received:2007-07-16 Revised:2007-12-11 Online:2008-09-25 Published:2008-09-25
  • Contact: Hong YOU

摘要: 腺相关病毒(AAV)编码的非结构蛋白Rep78/68具有抑制病毒和肿瘤转化的作用,并且对宿主细胞的增殖及代谢产生广泛地影响。本文将对此蛋白的最新研究进展进行综述。

关键词: Rep78/68蛋白, 腺相关病毒, 肿瘤

Abstract: Rep78/68 is a nonstructural protein of adeno-associated virus. It has been found to inhibit a variety of viruses and tumor transformation. In addition, it has spreading effect on the proliferation and metabolism of host cells. Here, we reviewed the latest advances of this protein.

Key words: Rep78/68 protein, adeno-associated virus, tumor