基础医学与临床 ›› 2010, Vol. 30 ›› Issue (10): 1109-1111.

• 短篇综述 • 上一篇    下一篇

间充质干细胞治疗急性胰腺炎的研究进展

薛小军 涂小煌 陈少全   

  1. 南京军区福州总医院 南京军区福州总医院
  • 收稿日期:2009-11-05 修回日期:2009-12-05 出版日期:2010-10-05 发布日期:2010-10-05
  • 通讯作者: 涂小煌

Progress in the Treatment of Acute Pancreatitis with Mesenchymal Stem Cells

Xiao-jun XUE, Xiao-huang TU, Shao-quan CHEN   

  1. Fuzhou General Hospital of Nanjin Military Command Fuzhou General Hospital of Nanjin Military Command
  • Received:2009-11-05 Revised:2009-12-05 Online:2010-10-05 Published:2010-10-05
  • Contact: Xiao-huang TU,

摘要: 间充质干细胞具有强大的免疫调节能力和促进组织修复的巨大潜能。在急性胰腺炎的发病过程能够抑制T、B淋巴细胞及多种炎症因子,并能"归巢"至损伤胰腺,促进损伤胰腺组织修复,参与了急性胰腺炎的病理生理过程。本文将对间充质干细胞在急性胰腺炎病程中的作用作一综述。

关键词: 间充质干细胞, 急性胰腺炎, 免疫调节, 修复

Abstract: Recent studies have shown that mesenchymal stem cells (MSCs) have immunomodulatory properties and tissue repairing potential. In the process of acute pancreatitis, MSCs suppress T cells and B cells and many kinds of inflammatory factors, and home to injuried pancreas to promote pancreatic tissue repairing. MSCs play an important role in pathophysiolgical progresses of acute pancreatitis. The review is on the effect of MSCs on acute pancreatitis.

Key words: mesenchymal stem cells, acute pancreatitis, immunomodulation, repair