基础医学与临床 ›› 2018, Vol. 38 ›› Issue (8): 1163-1167.
• 短篇综述 • 上一篇 下一篇
刘阳1,陈冉2,于世家1,文涛3
收稿日期:
修回日期:
出版日期:
发布日期:
通讯作者:
基金资助:
Received:
Revised:
Online:
Published:
摘要： 随着饮食结构和生活方式的改变，2型糖尿病合并非酒精性脂肪肝的病人不断增多，其发病机制中相关分子包括FGF21、Fetuin-A、SREBP-1、PPARα、IGFBP-1、IGF-1、TNF-α、CTRP3和AMPK等。期待不久的将来可以针对其分子靶点研发出高效的治疗非酒精性脂肪肝的药物。
关键词: 2型糖尿病, 非酒精性脂肪肝 , 分子机制
Abstract: With the change of diet structure and lifestyle, the number of type 2 diabetic patients with non-alcoholic fatty liver has been increasing. The relevant molecules in the pathogenesis include FGF21, Fetuin-A, SREBP-1, PPARα, IGFBP-1, IGF-1, TNF-α, CTRP3, and AMPK. It is expected that in the near future, highly effective drugs for the treatment of non-alcoholic fatty liver can be developed for its molecular targets.
Key words: type 2 diabetes, non-alcoholic fatty liver, molecular mechanism
中图分类号:
R969
刘阳 陈冉 于世家 文涛. 2型糖尿病合并非酒精性脂肪肝发病机制的研究进展[J]. 基础医学与临床, 2018, 38(8): 1163-1167.
0 / / 推荐
导出引用管理器 EndNote|Reference Manager|ProCite|BibTeX|RefWorks
链接本文: http://journal11.magtechjournal.com/Jwk_jcyxylc/CN/
http://journal11.magtechjournal.com/Jwk_jcyxylc/CN/Y2018/V38/I8/1163
