基础医学与临床 ›› 2016, Vol. 36 ›› Issue (7): 1014-1016.

• 临床园地 • 上一篇    下一篇

35例肾上腺嗜铬细胞瘤/副神经节瘤3D腹腔镜手术分析

文进1,李汉忠2,纪志刚1   

  1. 1. 中国医学科学院 北京协和医学院 北京协和医院
    2. 北京协和医院
  • 收稿日期:2016-03-07 修回日期:2016-05-20 出版日期:2016-07-05 发布日期:2016-06-22
  • 通讯作者: 李汉忠 E-mail:lhzjxmc@163.com
  • 基金资助:
    2012年国家临床重点专科建设项目基金

3D laparoscopic surgery for adrenal pheochromocytoma / paraganglioma:35 cases report

  • Received:2016-03-07 Revised:2016-05-20 Online:2016-07-05 Published:2016-06-22

摘要: 目的 探讨3D腹腔镜肾上腺嗜铬细胞瘤/副神经节瘤切除术的有效性和安全性。 方法 分析北京协和医院2013年1月-2015年11月成功实施的3D腹腔镜肾上腺嗜铬细胞瘤/副神经节瘤切除术35例,术前行内分泌、影像学及核医学等检查,并服用2-4周α受体拮抗剂。 对照组为2003年2月-2010年2月,北京协和医院实施的2D腹腔镜肾上腺嗜铬细胞瘤/副神经节瘤切除术,共211例(p<0.05)。结果 手术全部成功,2组肿瘤直径、术中出血量和住院时间无显著差异。3D组手术时间显著低于2D组。肾上腺嗜铬细胞瘤24例、副神经节瘤11例。3D组随访3月到30月,无复发和转移。 结论 与传统腹腔镜手术相比,3D腹腔镜成像系统在空间定位及深度感觉上有明显优势,手术安全可靠并且显著缩短手术时间。

关键词: 3D腹腔镜, 手术, 嗜铬细胞瘤, 副神经节瘤

Abstract: Abstract:Object To highlight the effectivity and safety of 3D-laparoscopic surgery to adrenal pheochromocytomas /paragangliomas. Methods 24 cases of adrenal pheochromocytomas and 11 paragangliomas proven pathologically from 2013 to 2015were treated by 3D-laparoscopic surgery. Endocrine secretion examinations , B-US , CT, MRI , 131IMIBG ,and octreotide were used to diagnose the diease. Patients took α-receptor blocker for 2-4 weeks preoperatively. 211 patients from 2003 to 2010 by 2D laparoscopic surgery were compared . Results All the operations were completed successfully. There were no major intraoperative complications. Mean tumor diameter in 3D group was (4.12±1.95)cm and (3.97±2.21)cm in 2D group , without significant difference (P>0.05). Mean estimated blood loss in 3D group was (57.8±35.3)ml and (84.6±56.3) ml in 2D group , without significant difference (P>0.05).Mean hospital stay after operation in 3D group was (3.9±1.3) d and (4.9±1.6) d in 2D group without significant difference (P>0.05) . Mean operating time in 3D group was (69±19)min and ( 97±29) min in 2D group, with significant difference (P <0.05).They were followed up for 3-30months. There were no recurrences of tumor .Conclusions 3D-laparoscopic surgery has obvious advantage in spatial location and the sense of depth for adrenal pheochromocytomas /paragangliomas ,which make the operation easier and shortens the operation time obviously.

Key words: three-dimensional imaging laparoscopy, sugery, pheochromocytoma, paraganglioma