基础医学与临床 ›› 2015, Vol. 35 ›› Issue (8): 1134-1138.
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孙平风,傅芬
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摘要: 多重连接探针扩增(MLPA)技术应用于检测肿瘤相关基因大片段缺失/重复,不仅有助于了解潜在的肿瘤发展分子机制,而且为肿瘤的诊断和预后提供重要信息,成为肿瘤学研究的主要方向。
关键词: MLPA, 肿瘤相关基因, 缺失/重复, 检测
Abstract: The multiplex ligation-dependent probe amplification (MLPA) technology used in detection of gene deletions/duplications not only helps in understanding the molecular mechanisms underlying the development of cancer, but also provides important information for disease diagnosis and prognosis. Currently, MLPA becomes a hotspot to be applied in testing tumor related gene deletions/duplications mutations.
Key words: MLPA, Tumor related gene, Deletions/duplications, Detection
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Q341
孙平风 傅芬. 多重连接探针扩增技术在肿瘤相关基因缺失/重复检测中的应用进展[J]. 基础医学与临床, 2015, 35(8): 1134-1138.
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