基础医学与临床 ›› 2011, Vol. 31 ›› Issue (4): 414-416.

• 研究论文 • 上一篇    下一篇

蒙古族家族性脑卒中一大家系临床特点

白海花1,邱长春2,包布仁巴乙拉1,吴慧光1,吴柒柱1   

  1. 1. 内蒙古民族大学
    2. 中国医学科学院基础医学研究所
  • 收稿日期:2010-04-19 修回日期:2010-05-25 出版日期:2011-04-05 发布日期:2011-04-08
  • 通讯作者: 吴柒柱 E-mail:qizhu_wu@sohu.com
  • 基金资助:
    省自然科学基金

The clinical features of stroke in Mongolian family

Hai-hua BAI1,Chang-chun QIU2,Buren-bayaer BAO3,Hui-guang WU3,Qi-zhu WU1   

  1. 1. Inner Mongolia University for the Nationalities
    2. IBMS, CAMS & PUMC
    3.
  • Received:2010-04-19 Revised:2010-05-25 Online:2011-04-05 Published:2011-04-08
  • Contact: Qi-zhu WU E-mail:qizhu_wu@sohu.com

摘要: 目的 探讨蒙古族家族性脑卒中一大家系的临床特点。方法 本文采用临床检查与家系调查相结合的方法对该蒙古族家系进行系统分析,对已发病的脑卒中患者进行CT或MRI检查进一步确诊,采取血液样本各10 ml(5 ml抗凝血,5ml未抗凝血)进行相关生理生化指标以及致病基因研究。结果 该家系共137名成员。脑卒中患者10名,高血压/高血脂异常患者16名。血脂检查结果表明患者组甘油三酯、总胆固醇值显著高于正常组(p<0.05),高密度脂蛋白显著低于正常组(p<0.05)。结论:血脂异常和高血压是该家系脑卒中发病的主要原因。

关键词: 蒙古族, 脑卒中, 临床特点

Abstract: Object: To explore the clinical specialty of stroke in Mongolian family .Methods: The pedigree was analyzed along with physical examination, stroke patients were been diagnose by CT or MRI, pick sample of blood 10ml to check the correlative physiological and biochemical criterion and gene research. Result:This family has 137 individuals, and including 10 strock patients 16 hypertension/ hyperlipoidemia patients, the result of blood fat diagnose indicated that the triglyceride’s and total cholesterol’s means of patients is higher than control group(p<0.05) ,and the HDL is lower than control group(p<0.05). Conclusion: The abnormity of blood fat and hypertension are main reason of the stroke.

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