基础医学与临床 ›› 2021, Vol. 41 ›› Issue (3): 448-451.

• 短篇综述 • 上一篇    下一篇

肿瘤微环境在骨癌痛中作用的新进展

周佳宏1,李民2   

  1. 1. 北京大学第三医院
    2. 北京大学第三医院麻醉科
  • 收稿日期:2020-08-07 修回日期:2020-12-06 出版日期:2021-03-05 发布日期:2021-03-01
  • 通讯作者: 李民 E-mail:liminanesth@yahoo.com.cn

Advances on the roles of tumor microenvironment in bone cancer pain

Jia-Hong ZHOU1,LI Min   

  • Received:2020-08-07 Revised:2020-12-06 Online:2021-03-05 Published:2021-03-01
  • Contact: LI Min E-mail:liminanesth@yahoo.com.cn

摘要: 肿瘤微环境是肿瘤在人体中赖以生存的微环境,骨癌痛是肿瘤骨转移最常见的并发症之一。骨癌痛的机制复杂,肿瘤酸性微环境、相关离子通道及肿瘤细胞在微环境中分泌的炎性介质在骨癌痛中起作用。

关键词: 肿瘤微环境, 骨癌痛, 炎性介质

Abstract: Tumor microenvironment is the microenvironment in which tumors live in human body. Cancer-induced bone pain is one of the most common symptoms of tumor bone metastasis, . The mechanisms of bone cancer pain are complex, and the tumor acidic microenvironment, the related ion channels and inflammatory mediators released by cancer, play a role in bone cancer pain.

Key words: tumor microenvironment, bone cancer pain, inflammatory mediators

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