基础医学与临床 ›› 2019, Vol. 39 ›› Issue (3): 404-408.

• 短篇综述 • 上一篇    下一篇

长链非编码RNA尿路上皮癌胚抗原1在肝癌中表达的研究进展

师丽,王宇   

  1. 陕西中医药大学
  • 收稿日期:2018-03-16 修回日期:2018-07-01 出版日期:2019-03-05 发布日期:2019-03-05
  • 通讯作者: 王宇 E-mail:wangyu541ban@sina.com
  • 基金资助:
    国家自然科学基金

Research progress of long non-coding RNA UCA1 in hepatocellular carcinoma

Li SHI1,   

  • Received:2018-03-16 Revised:2018-07-01 Online:2019-03-05 Published:2019-03-05

摘要: 肝癌(HCC)是全球发病率排名第六,病死率排名第三的恶性肿瘤,严重危害人类的健康。长链非编码RNA(lncRNA)尿路上皮癌胚抗原1(UCA1)在肝癌的增殖,分化、转移和预后等方面有着重要作用,进一步丰富了肝癌发生发展机制,为肝癌的诊断治疗提供了新思路。

关键词: 长链非编码RNA, 尿路上皮癌胚抗原1, 肝癌

Abstract: Hepatocellular carcinoma (HCC) is the sixth most common malignant tumor in the world with the third highest mortality rate, which seriously endangers human health. Long non-coding RNA(lncRNA) urothelial cancer associated 1 (UCA1) plays an important role in the proliferation, differentiation , metastasis and prognosis of hepatocellular carcinoma onset and progression. In recent years, an abundance of studies and researches have shown that the up-regulated expression of UCA1 makes a significance to enrich the development of HCC and provide a new way of thinking for the diagnosis and treatment of HCC .

Key words: Long non-coding RNA , urothelial cancer associated 1, hepatocellular carcinoma

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