基础医学与临床 ›› 2018, Vol. 38 ›› Issue (6): 840-844.
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何芳1,秦青青2,郑永钦3,贺军栋3
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摘要: microRNA(miRNA)是一类高度保守的内源性小型非编码调控核糖核酸,肿瘤发生和发展的关键调节因子。miR-338在大多数肿瘤中异常表达,其异常表达能够影响肿瘤细胞的增殖、侵袭、转移和血管发生等生理活动,并通过靶向调控一个或多个靶基因发挥作用。
关键词: 关键词:microRNA-338, 肿瘤, 研究进展
Abstract: MicroRNAs (miRNAs) are a class of highly conserved, endogenous, small, non-coding RNAs that regulate RNAi and are key regulators of tumorigenesis and development.MiR-338 is abnormally expressed in most tumors. Aberrant expression of miR-338 can affect the proliferation, invasion, metastasis, angiogenesis and other physiological activities of tumor cells and play a vital role in the regulation on one or more target-genes.
Key words: Keywords: microRNA-338, tumor, research progress
中图分类号:
R73
何芳 秦青青 郑永钦 贺军栋. miR-338在肿瘤中的研究进展[J]. 基础医学与临床, 2018, 38(6): 840-844.
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