基础医学与临床 ›› 2017, Vol. 37 ›› Issue (6): 865-869.

• 研究论文 • 上一篇    下一篇

临床药师干预临床抗菌药物使用后的效果分析

盛垚1,冯华2,李景云2   

  1. 1. 广东省中山市小榄人民医院
    2. 广东省中山市南朗医院
  • 收稿日期:2017-04-12 修回日期:2017-04-21 出版日期:2017-06-05 发布日期:2017-05-26
  • 通讯作者: 盛垚 E-mail:xlyshengyao@sina.com

Outcome evaluation of clinical pharmacists intervention on clinical antimicrobial agents

  • Received:2017-04-12 Revised:2017-04-21 Online:2017-06-05 Published:2017-05-26

摘要: 目的 探讨临床药师干预结合指标管理在临床使用抗菌素中的作用。方法回顾临床药师干预后(2016年1月至2016年11月)与干预前(2015年同期)医院住院及门诊患者抗菌药物的使用率、使用强度、微生物检验样本送检率和清洁手术预防用抗菌药物的情况,并进行统计学分析。结果:与干预前相比,干预后住院患者抗菌药物使用率(50.02%)及门诊患者抗菌药物总使用率(25.72%)均低于干预前(P<0.05,分别为52.55%和30.05%);抗菌药物使用强度50.59%也低于干预前的使用强度62.39%(P<0.05)。同时,微生物样本送检率(27.49%)高于干预前13.96%,(P<0.05);清洁切口抗菌药物使用率每月均呈下降趋势;抗菌药物的品种选择、给药时机、给药时间的合理率均呈上升趋势。结论 临床药师的专业干预更有利于抗菌药物临床应用工作日常化、规范化和专业技术化,促进用药合理性和医院药学的发展。

关键词: 临床药师, 干预, 抗菌药物, 使用, 效果分析.

Abstract: Objective To investigate the effects of clinical pharmacist intervention in the clinical application of antibiotics combined with the index management. Methods The data of antibiotics usage rate and intensity, the microbial test sample submission rate, and the clean incision preventive usage rate of inpatients and outpatients were analyzed by chi-square test in the same period before (2015) and after (2016) the clinical pharmacist intervention. Results After intervention, the antibiotics usage rate of inpatients and outpatients were lower than that of 2015 (50.02% and 25.72%, P<0.05). In 2016, the usage intensity of antibiotics was 50.59%, while it was 62.39% in 2015. At the same time, the microbial test sample submission rate increased from 13.96% to 27.49% (P<0.05).In 2016, the clean operation preventive usage rate of antibiotics decreased month by month. In the meantime, the reasonable rate of delivery timing, variety selection, and administration time of clean operation preventive usage of antibiotics were on the rise. Conclusion The professional intervention of clinical pharmacist is benefit for the routine, standardization, and professionalization of clinical antibiotics application.It also promotes the rational use of drugs and the progress of hospital pharmacy.

Key words: Key words: Clinical pharmacists, Intervention, Antimicrobial agents, Use, Effect analysis