基础医学与临床 ›› 2017, Vol. 37 ›› Issue (11): 1634-1639.
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胡洋洋1,卢海妹1,刘亚坤2,姜玉3,阚立新1
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摘要: 获得性异位骨化(aHO)是指正常骨骼系统之外出现的异常骨组织。aHO的创伤来源丰富且病因复杂,BMP信号通路、Hedgehog信号通路、Wnt/β-catenin信号通路和NF-κB信号转导通路在aHO的致病过程中发挥重要作用。
关键词: 获得性异位骨化(aHO), 信号通路, 致病机理
Abstract: Acquired heterotopic ossification is the abnormal bone formation outside of the normal skeletal system .The origin trauma and disease of aHO is plentiful. In this review, we focus on BMP,hedgehog,wnt/β-catenin and NF-κB signaling pathway, understanding of the pathogenesis of aHO.
Key words: acquired heterotopic ossification , signaling pathway, pathogenesis
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R363
胡洋洋 卢海妹 刘亚坤 姜玉 阚立新. 获得性异位骨化的研究进展[J]. 基础医学与临床, 2017, 37(11): 1634-1639.
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http://journal11.magtechjournal.com/Jwk_jcyxylc/CN/Y2017/V37/I11/1634