基础医学与临床 ›› 2016, Vol. 36 ›› Issue (1): 121-124.

• 短篇综述 • 上一篇    下一篇

库欣综合征所致高凝状态的研究进展

吴遐1,高路2,幸兵2   

  1. 1. 中国医学科学院 北京协和医学院
    2. 北京协和医院
  • 收稿日期:2015-07-06 修回日期:2015-09-30 出版日期:2016-01-05 发布日期:2015-12-29
  • 通讯作者: 幸兵 E-mail:xingbingemail@aliyun.com
  • 基金资助:
    首都临床特色应用研究

Research progress on hypercoagulable state in Cushing’s syndrome

  • Received:2015-07-06 Revised:2015-09-30 Online:2016-01-05 Published:2015-12-29
  • Contact: Bing XING E-mail:xingbingemail@aliyun.com

摘要: 库欣综合征是高皮质醇血症所致的临床症候群,该病患者常合并高凝状态,其动静脉血栓事件、心血管病发生率乃至死亡率均高于普通人群。本文将介绍库欣综合征高凝状态的病理生理机制,并对临床上预防性使用抗凝药物提供指导。

关键词: 库欣综合征, 高凝状态, 静脉血栓栓塞症

Abstract: Cushing’s syndrome (CS) results from chronic exposure to excessive levels of glucocorticoids. Generally it is accompanied by a hypercoagulable state. Patients with CS have a higher risk of arterial and venous thrombotic events, cardiovascular disease morbidity and mortality. This review aims to introduce its pathophysiological mechanisms, and to provide examples and guidelines for antithrombotic prophylaxis in CS.

Key words: Cushing’s syndrome, hypercoagulable state, venous thromboembolism

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