基础医学与临床 ›› 2015, Vol. 35 ›› Issue (6): 842-845.
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熊焱强1,刘朝奇2,李志英3
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摘要: 微小RNA(miRNA)在宫颈癌的发生、侵袭、转移和复发等过程中扮演重要角色,与其预后密切相关。宫颈癌患者血清中异常表达的miRNA可作为其无创诊断和预后判断的生物标记物,通过研究血清miRNA可以早期诊断宫颈癌,减少肿瘤的转移和复发,寻找治疗靶点,为宫颈癌的诊疗提供突破点。
关键词: 宫颈癌, miRNA, 早期诊断, 预后
Abstract: MicroRNA play an important role in the process of cervical cancer incidence, invasion, metastasis and recurrence, and closely related to its prognosis. The abnormal expression of miRNAs in cervical cancer patients’s serum can be used as a noninvasive diagnostic and prognostic biomarkers.Based on studies of serum microRNAs, the early presence of cervical cancer can be detected, reduce tumor metastasis and recurrence, search for therapeutic targets, tumor recurrence are reduced, and find targets and breakthrough in diagnosis and treatment of cervical cancer.
Key words: cervical cancer, miRNA, early diagnosis, prognosis
中图分类号:
R737.33
熊焱强 刘朝奇 李志英. miRNA在宫颈癌早期诊断及预后中的研究进展[J]. 基础医学与临床, 2015, 35(6): 842-845.
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