基础医学与临床 ›› 2015, Vol. 35 ›› Issue (4): 541-544.

• 短篇综述 • 上一篇    下一篇

微小RNA与心房颤动心房纤维化

蒋智渊,钟国强   

  1. 广西医科大学第一附属医院
  • 收稿日期:2014-10-15 修回日期:2014-11-27 出版日期:2015-04-05 发布日期:2015-04-08
  • 通讯作者: 钟国强 E-mail:gq_zhong@126.com
  • 基金资助:
    广西自然科学基金

The association between microRNAs and atrial fibrosis in atrial fibrillation

  • Received:2014-10-15 Revised:2014-11-27 Online:2015-04-05 Published:2015-04-08

摘要: 心房纤维化是心房颤动(房颤)发生与维持的重要因素,微小RNA(microRNA, miRNA)通过调控纤维化相关靶基因,在房颤心房纤维化中起着重要作用。因此,深入研究miRNA在心房纤维化中的作用机制将为房颤的诊治提供新的思路。

关键词: 微小RNA, 心房颤动, 心房纤维化

Abstract: Atrial fibrosis plays an important role in atrial fibrillation (AF). MicroRNAs(miRNAs) contribute to atrial fibrosis by targeting the genes related to fibrosis. Therefore, the study on the mechanistic association between miRNAs and atrial fibrosis may provide new insights for diagnosis and treatment of atrial fibrillation.

Key words: microRNA, atrial fibrillation, atrial fibrosis

中图分类号: