液体负荷试验结合胃内压评价健康人近端胃功能

基础医学与临床 ›› 2014, Vol. 34 ›› Issue (7): 886-890.

液体负荷试验结合胃内压评价健康人近端胃功能

邓莉¹,柯美云²,姚树坤³,王智凤⁴,陈彦文⁵,孙晓红⁶,方秀才⁴,朱丽明⁴

1. 北京协和医学院研究生院，中日友好医院消化内科
2. 中国医学科学院北京协和医学院北京协和医院
3. 卫生部中日友好医院
4. 中国医学科学院北京协和医学院北京协和医院消化内科
5. 上海瑞金医院
6. 北京协和医院

收稿日期:2013-12-30 修回日期:2014-03-27 出版日期:2014-07-05 发布日期:2014-06-24
通讯作者: 姚树坤 E-mail:yao.sk@hbmu.edu

Evaluation of proximal stomach function by simultaneous determination of intra-gastric pressure in perfusion nutrient load test

Received:2013-12-30 Revised:2014-03-27 Online:2014-07-05 Published:2014-06-24

摘要/Abstract

摘要： 目的与“金标准”恒压器相比，灌注法液体营养负荷试验（PNLT）结合胃内压（IGP）测定在健康志愿者（HS）近端胃功能中的意义。方法 30例HS在不连续的2d中，分别行PNLT结合IGP测定和恒压器检查。通过VAS评分，分别记录HS不同饱感即初始饱感、轻度饱感、中度饱感、明显饱感、最大饱感时的压力和容积。结果不同饱感时的压力和容积在两种方法之间均有一定的相关性；另外PNLT结合IGP最大饱感时胃内压与恒压器试餐后胃容受性、容受性舒张呈一定程度的正相关（P<0.05)，最大饱感时灌注量与恒压器试餐后平均胃内容积呈一定程度的正相关（P<0.05）。结论 PNLT结合IGP测定与恒压器具有一定的可比性，具有良好的可行性，安全性和可靠性，可用于评价近端胃功能。

关键词: 液体营养餐, 负荷试验, 近端胃

Abstract: Objective To extensively evaluate the method of simultaneous determination of intra-gastric pressure (IGP) in perfusion nutrient load test (PNLT) in HS. Methods 30 HS were recruited. All HS were received simultaneous determination of IGP in PNLT. The barostat study was completed in another day. Visual analogue scale (VAS) was used to evaluate satiety during simultaneous determination of IGP in PNLT and the barostat study. Finally, all totally data were collected and analyzed. Results Pressure and volume of different satiety evaluated by VAS had significant correlation between the two methods respectively；IGP at maximal satiety was significantly correlated with peak accommodation volume and meal induced relaxation volume by the barostat study (P<0.05)；Maximal perfusion volume has significantly correlated with gastric postprandial averaged volume by the barostat study (P<0.05). Conclusions The method of simultaneous determination of IGP in PNLT has excellent feasibility, safety and reliability, and could be useful for evaluating proximal stomach function.

Key words: liquid nutrient , load test, proximal stomach

中图分类号:

R573.9

邓莉柯美云姚树坤王智凤陈彦文孙晓红方秀才朱丽明. 液体负荷试验结合胃内压评价健康人近端胃功能[J]. 基础医学与临床, 2014, 34(7): 886-890.