基础医学与临床 ›› 2014, Vol. 34 ›› Issue (7): 1002-1005.

• 短篇综述 • 上一篇    下一篇

卵巢功能早衰中端粒及端粒酶作用的研究进展

王伟聿1,唐莉2   

  1. 1. 昆明理工大学
    2. 云南省第一人民医院
  • 收稿日期:2014-03-20 修回日期:2014-05-19 出版日期:2014-07-05 发布日期:2014-06-24
  • 通讯作者: 唐莉 E-mail:tanglikm@163.com

The research advances in the role of telomere/telomerase in premature ovarian failure

Wei-Yu WANG1,   

  • Received:2014-03-20 Revised:2014-05-19 Online:2014-07-05 Published:2014-06-24

摘要: 卵巢功能与卵泡内卵细胞和颗粒细胞的分裂、增殖和分化密切相关。端粒作为细胞分裂能力的“分子钟”,在各类真核细胞的分裂增殖过程中发挥了重要的作用。

关键词: 卵巢功能早衰, 端粒, 端粒酶, 细胞增殖分化

Abstract: Ovarian function has close association with division, proliferation and differentiation of oocytes and granulosa cells in ovary. Telomere, as a molecular clock measuring the ability of cell division, plays a critical role in division and differentiation of variant eukaryotic cells. Recent researches summerized premature ovarian failure based on telomere and telomerase.

Key words: Premature ovarian failure, telomere, telomerase, division and differentiation of cell

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