基础医学与临床 ›› 2014, Vol. 34 ›› Issue (12): 1655-1657.

• 研究论文 • 上一篇    下一篇

纤连蛋白(FN)治疗口腔溃疡

王斌1,张世阳1,桑喜成1,李海波2,许义辉1,杨敏祺3   

  1. 1. 郑州弗博瑞生物技术有限公司
    2. 河南省中医院内科
    3. 上海伊皓生物技术有限公司
  • 收稿日期:2014-05-15 修回日期:2014-07-16 出版日期:2014-12-05 发布日期:2014-11-25
  • 通讯作者: 张世阳 E-mail:609749236@qq.com
  • 基金资助:
    科技部科技型中小企业创新基金

Fibronectin(FN) in treatment of mouth ulcer

  • Received:2014-05-15 Revised:2014-07-16 Online:2014-12-05 Published:2014-11-25

摘要: 目的 观察纤连蛋白(FN)在口腔溃疡治疗中的效果。方法 将150例口腔溃疡患者,随机均分为给予纤连蛋白治疗的观察组和给予冰硼散治疗对照组,观察临床效果。结果 观察组溃疡面积、充血面积缩小程度明显大于对照组(P<0.05)。观察组自发痛、烧灼痛及激惹痛缓解程度明显大于对照组(P<0.05)。结论:纤连蛋白治疗口腔溃疡疗效显著,可以快速促进溃疡面愈合,而且非常安全,无副作用,值得在临床工作中推广。

关键词: 纤连蛋白, 口腔溃疡, 治疗

Abstract: Objective To observe the effect of FN in the treatment of mouth ulcer.Methods The patients(n=150) were randomly divided into FN group and control group.Results The reduction of ulce and congestion area of FN group were significantly greater than that of the control group(P<0.05). The degree of pain relief of spontaneous pain,burning pain and bowel pain were significantly greater than that of the control group(P<0.05).Conclusions FN treatment for mouth ulcer is effective and safe,and has great clinical value.

Key words: fibronectin, mouth ulcer, treatment

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