基础医学与临床 ›› 2013, Vol. 33 ›› Issue (3): 374-377.

• 短篇综述 • 上一篇    下一篇

线粒体对iPSC再程序化的影响

贺文凤1,曹青1,洪葵2   

  1. 1. 南昌大学第二附属医院
    2. 南昌大学第二附属医院分子医学实验室
  • 收稿日期:2012-05-03 修回日期:2012-06-28 出版日期:2013-03-05 发布日期:2013-03-05
  • 通讯作者: 洪葵 E-mail:hongkui88@163.com
  • 基金资助:
    国家973项目;教育部创新团发展计划

The effect of mitochondria on the iPSC reprogramming

  • Received:2012-05-03 Revised:2012-06-28 Online:2013-03-05 Published:2013-03-05

摘要: iPS技术的出现为研究疾病的发病机制、药物筛选以及再生医学提供了新的途径。尽管iPS技术取得了迅速的发展,但对于iPS重编程过程目前仍不清楚。线粒体是细胞的多种生理过程的重要参与者,而其与iPS再程序化过程有什么联系,起到什么样的作用仍有待研究。

关键词: iPS, 线粒体, 再程序化

Abstract: iPS provides a new way for the study of disease pathogenesis,drug discovery and regenerative medicine.Despite the rapid progress has been made in the iPS cell technology,the reprogramming of iPS is still unclear.Mitochondria is an important participant in various physiological processes in the cell.The effect of mitochondria on the iPS reprogramming and the relationship between them need to be studied.

Key words: iPS, mitochondria, reprogramming

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