基础医学与临床 ›› 2011, Vol. 31 ›› Issue (12): 1406-1409.

• 短篇综述 • 上一篇    下一篇

转移相关基因在肿瘤中的研究进展

曹磊1,任华2   

  1. 1. 中国医学科学院北京协和医院
    2. 北京协和医院
  • 收稿日期:2010-10-11 修回日期:2011-03-03 出版日期:2011-12-05 发布日期:2011-12-05
  • 通讯作者: 任华 E-mail:renjohnh@yahoo.com.cn

The development of research of Metastasis-Associated Gene in human cancer

  • Received:2010-10-11 Revised:2011-03-03 Online:2011-12-05 Published:2011-12-05

摘要: 转移相关基因(metastasis-associated gene, MTA)是一个与肿瘤发生、进展和转移等密切相关的基因家族,其成员编码蛋白在多种人类肿瘤细胞中异常升高。最近的研究表明,转移相关基因可能是多种恶性肿瘤发生与进展相关的主要调节分子。本文针对目前转移相关基因在恶性肿瘤发生与进展过程中分子机制的研究及其在临床诊治中的应用做一综述。

关键词: 转移相关基因, 肿瘤

Abstract: Abstract: MTA is a gene family closely related with carcinogenesis and cancer progression whose member overexpressed in a wide range of human cancers. According to many studies recently, MTA may be one of main regulatory molecules in the procession of carcinogenesis and progression. This review is about the new development of research of MTA and its clinical application in the future.

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