基础医学与临床 ›› 2008, Vol. 28 ›› Issue (5): 507-510.

• 临床园地 • 上一篇    下一篇

404例结肠癌的临床病理及随访

吕洋 刘博 任君旭 吴靖芳 赵坡 薛 刚   

  1. 河北北方学院组胚教研室 河北医科大学附属第四医院病理科 河北北方学院组胚教研室 河北北方学院组胚教研室 解放军总医院病理科 河北北方学院附属第一医院耳鼻咽喉-头颈外科
  • 收稿日期:2007-10-16 修回日期:2007-11-28 出版日期:2008-05-25 发布日期:2008-05-25
  • 通讯作者: 薛 刚

Clinicopathologic and prognostic study on 404 cases of colon cancer

Yang LU, Bo LIU, Jun-xu REN, Jing-fang WU, Po ZHAO, Gang XUE   

  1. Hebei North University First Affiliated Hospital of Hebei North University
  • Received:2007-10-16 Revised:2007-11-28 Online:2008-05-25 Published:2008-05-25
  • Contact: Gang XUE

摘要: 目的 通过对404例结肠癌患者的分析,探讨其临床病理特征及影响患者术后生存的因素。方法 回顾性研究1993~2003年间在解放军总医院行手术治疗的404例结肠癌患者(其中209例获得完整的随访资料)的临床、病理资料,进行单因素及多因素分析。结果 ⑴单因素分析显示,患者发病年龄、肿瘤的分化程度、淋巴结转移情况、腹腔及远处转移情况、肿瘤的病理分期及患者术后是否进行放化疗等均为影响预后的因素。⑵多因素回归分析表明腹腔及远处转移以及肿瘤的病理分期是影响患者术后生存的独立因素。结论:影响结肠癌患者术后生存的独立因素仅为腹腔及远处转移情况以及肿瘤的病理分期。

关键词: 结肠癌, 预后, 多因素分析

Abstract: Objective This study was undertaken to identify clinicopathologic characteristics and prognostic factors through a retrospective analysis of 404 colon cancer patients. Methods A total of 404 patients (209 of them were followed up with inquisition) with colonl cancer, which were treated surgically during a period from 1993 to 2003, were studied by univariate and multivariate analysis. Results ⑴ Using univariate analysis age of patients, differentiation degree of the tumors, lymphatic invasion, abdominal and distant metastases, TNM stage and adjuvant radiotherapy were associated with outcome. ⑵Using multivariate analysis only abdominal and distant metastases and TNM stage were associated with prognosis. Conclusions Multivariate analysis revealed the following independent prognostic factors: abdominal and distant metastases and TNM stage.

Key words: Colon cancer, Prognosis, Multivariate analysis