基础医学与临床 ›› 2023, Vol. 43 ›› Issue (4): 656-659.doi: 10.16352/j.issn.1001-6325.2023.04.0656

• 疑难病例 • 上一篇    下一篇

库欣综合征术后继发于亚急性甲状腺炎的甲状腺危象1例报道

余洁, 黄奇彬, 李玉秀, 李梅, 连小兰, 平凡*   

  1. 中国医学科学院 北京协和医学院 北京协和医院 内分泌科 卫健委内分泌重点实验室, 北京 100730
  • 收稿日期:2021-12-13 修回日期:2022-06-05 出版日期:2023-04-05 发布日期:2023-04-03
  • 通讯作者: *pingfan6779@163.com
  • 基金资助:
    上海市医药卫生发展基金会糖尿病临床研究项目(Ⅱ期09研究)

Thyroid storm caused by subacute thyroiditis after Cushing's syndrome remission:one case report

YU Jie, HUANG Qibin, LI Yuxiu, LI Mei, LIAN Xiaolan, PING Fan*   

  1. Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730,China
  • Received:2021-12-13 Revised:2022-06-05 Online:2023-04-05 Published:2023-04-03
  • Contact: *pingfan6779@163.com

摘要: 患者为46岁女性,因库欣综合征5月前行肾上腺腺瘤切除术,予糖皮质激素替代逐步减量中,3周前因咽痛、饮水呛咳、恶心、呕吐自行停药。之后出现高热及意识障碍,化验提示甲状腺功能亢进,予丙硫氧嘧啶及β受体阻滞剂后意识障碍进行性加重,结合炎性指标升高、TSH受体抗体阴性及摄碘率低平考虑为亚急性甲状腺炎,加用糖皮质激素治疗后病情好转,甲亢缓解。

关键词: 甲状腺毒症, 甲状腺危象, 亚急性甲状腺炎, 库欣综合征

Abstract: A 46-year-old female was subjected to unilateral left adrenalectomy due to Cushing's syndrome 5 months ago. After surgery, she was placed on glucocorticoid substitution and discontinued the treatment due to nausea and vomiting 3 weeks ago. Then she developed subacute thyroiditis and progressed to thyroid storm. Her condition worsened after administration of propylthiouracil and β-blockers, but was soon relieved by administration of glucocorticoids.

Key words: thyrotoxicosis, thyroid storm, subacute thyroiditis, Cushing's syndrome

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