基础医学与临床 ›› 2023, Vol. 43 ›› Issue (2): 317-321.doi: 10.16352/j.issn.1001-6325.2023.02.317

• 短篇综述 • 上一篇    下一篇

外泌体lncRNA在结直肠癌液体活检中的研究进展

姚刘旭1,2, 李玉红3*, 蒋宗明1*   

  1. 1.绍兴市人民医院 麻醉科,浙江 绍兴 312000;
    2.绍兴文理学院 医学院,浙江 绍兴 312000;
    3.浙江树人大学树兰国际医学院附属树兰(杭州)医院 麻醉科,浙江 杭州 310004
  • 收稿日期:2021-08-27 修回日期:2022-04-07 出版日期:2023-02-05 发布日期:2023-02-02
  • 通讯作者: *yuh_li@zju.edu.cn; jiangzhejiang120@163. com
  • 基金资助:
    浙江省科学技术厅公益项目(Y21H150002,LGF19H030011);绍兴市人民医院青年科研基金项目(2020YB15);绍兴市公益项目(2020A13014);绍兴市麻醉学重点学科项目(2019SZD04)

Research progress of exosome lncRNA in liquid biopsy of colorectal cancer

YAO Liuxu1,2, LI Yuhong3*, JIANG Zongming1*   

  1. 1. Department of Anesthesiology, Shaoxing People’s Hospital, Shaoxing 312000;
    2. School of Medicine, Shaoxing University Shaoxing 312000;
    3. Department of Anesthesiology, Shulan Hospital (Hangzhou), Shulan International Medical College, Zhejiang Shuren University, Hangzhou 310004, China
  • Received:2021-08-27 Revised:2022-04-07 Online:2023-02-05 Published:2023-02-02
  • Contact: *yuh_li@zju.edu.cn; jiangzhejiang120@163. com

摘要: 目前针对结直肠癌(CRC) 的诊断技术仍在不断完善。液体活检主要对生物源液体特定成分进行分析,外泌体来源的长链非编码RNA (lncRNA)可以通过液体活检技术分析。

关键词: 结直肠癌, 液体活检, 外泌体, lncRNA, 生物标志物

Abstract: The diagnostic methods for colorectal cancer (CRC) are still improving. Liquid biopsy mainly analyzes the specific components of biological liquid. Long chain noncoding RNA (lncRNA) from exosomes can be analyzed by liquid biopsy technology.

Key words: colorectal cancer, liquid biopsy, exosome, lncRNA, biomarkers

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