OBJECTIVE To study the chemical constituents of acetyl acetate extracted fraction from Veratrum dahuricum. METHODS The compounds were isolated and purified by silica,Sephadex LH-20 and polyamide column chromatography and their structures were identified by physicochemical properties and spectral analysis.RESULTS Six compounds were isolated and identified as veramitaline(Ⅰ),germine(Ⅱ),veratrosine(Ⅲ),pseudojervine(Ⅳ) piceid(Ⅴ),mulberroside A(Ⅵ).CONCLUSION CompoundⅠ-ⅡandⅣ-Ⅵare isolated from V.dahuricum for the first time,and compoundⅥis firstly obtained from this genus.
NIE Li-yue;TNG Jin;LI Hui-ling;JIN Hui-zi;ZHNG Wei-dong;.
Studies on Chemical Constituents of Acetyl Acetate Extracted Fraction from Veratrum dahuricum[J]. Chinese Pharmaceutical Journal, 2008, 43(13): 971-973
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Chinese Materia Medica of State Administration of Traditional Chinese Medicine. Chinese Materia Medica(中华本草) [M] . Shanghai：Shanghai Science and Technology Press，1999，Vol.22：183-188.
[2] XU G J，XU L S，WANG Z T，et al.Species Systematization and quality Evaluation of Commonly Used Chinese Traditional Drugs(常用中药材品种整理和质量研究) [M] .4th ed. Fujian Science and Technology Press，Fujian，2001，121-178.
[3] QUAN X H，PIAO H S，SUN X H，et al.Studies on the chemical constituents of Veratrum dahuricum[J] .Chin Pharm J(中国药学杂志)，2003，38(12)： 914-916.
[4] TANG J，LI H L，SHEN Y H，et al.Four new germine esters from Veratrum dahuricum[J] .Helv Chim Acta，2007，90（4）：769-775.
[5] ZHOU C X，TAN R X. Steroidal alkaloids from Veratrum taliense[J] .Indian J Chem Sect B Org Chem Med Chem，2000，39：283-286.
[6] ELSAYED K A，MCCHESNEY J D，HALIM A F，et al.A study of alkaloids in Veratrum viride aition[J] .Int J Pharm，1996，34(3)： 161-173.
[7] ATTA-UR-RAHMAN A R，ASHRAF M，CHOUHARY M I，et al.Steroidal alkaloids from Veratrum album[J] . Phytochemistry，1996，43(4)：907-911.
[8] JAYATILAKE G S，JAYASURIYA H，LEE E S，et al.Kinase inhibitors from Polygonum cuspidatum[J] .J Nat Prod，1993，56(10)：1085-1810.
[9] HIRAKURA K，FUJIMOYO Y，FUKAI T，et al.Two new phenolic glycosides from the root bark of the cultivated muoberry tree(Morus lhou)[J] .J Nat Prod，1986，49(2)：218-224.
