Diet, gut microbiota and vascular calcification

doi:10.16352/j.issn.1001-6325.2025.02.0154

Abstract

Abstract: Gut microbiota, implicated in obesity, insulin resistance, depression, and cardiovascular risk, can be modulated by probiotics to mitigate cardiovascular disease risk. Vascular calcification (VC), a regulated process involving mineral deposits in vessels and valves, is a significant risk factor. Diet profoundly impacts both gut microbiota and VC, influencing cardiovascular health via microbial metabolites. While the link between gut microbiota and VC is established, the precise dietary effects on vascular health remain unclear. This article reviews mechanisms through which dietary patterns shape gut microbiota and metabolites, influence VC and highlights directions for future research on VC diagnosis and treatment.

Key words: gut microbiota, vascular calcification

CLC Number:

R541

LIU Yiming, CHEN Wenjie, SHI Yuchen, LIU Jinghua. Diet, gut microbiota and vascular calcification[J]. Basic & Clinical Medicine, 2025, 45(2): 154-159.

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