Research progress on the roles of angiopoietin-like protein 8 in the pathogenesis of cardiovascular diseases

doi:10.16352/j.issn.1001-6325.2024.04.0544

Abstract

Abstract: Angiopoietin-like protein 8(ANGPTL8) secreted by liver and adipose tissue, is a glycoprotein exerting paramount effects on facilitation of vascular remodeling and regulation of inflammatory response; ANGPTL8 is involved in the initiation and progression of cardiovascular diseases including coronary artery disease, hypertension, aortic aneurysm and pathological cardiac hypertrophy, and holds promise for being a new target for the prevention and treatment of cardiovascular diseases.

Key words: angiopoietin-like protein 8, coronary artery disease, hypertension, aortic aneurysm, pathological cardiac hypertrophy

CLC Number:

R363.1

HAN Lijie, HU Chaowei, YU Huahui, QIN Yanwen. Research progress on the roles of angiopoietin-like protein 8 in the pathogenesis of cardiovascular diseases[J]. Basic & Clinical Medicine, 2024, 44(4): 544-547.

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