Research progress on the role of transcription factor T-bet in the pathogenesis of chronic obstructive pulmonary disease

doi:10.16352/j.issn.1001-6325.2023.08.1322

Basic & Clinical Medicine ›› 2023, Vol. 43 ›› Issue (8): 1322-1325.doi: 10.16352/j.issn.1001-6325.2023.08.1322

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Research progress on the role of transcription factor T-bet in the pathogenesis of chronic obstructive pulmonary disease

CHEN Yuting¹, HUANG Ling^2*, XIA Junjie², QIU Yu², YI Ke³, WANG Jincheng⁴

1. Department of Respiratory and Critical Care Medicine, Clinical Medical College, Southwest Medical University, Luzhou 646000;
2. Department of Respiratory and Critical Care, the Third People's Hospital of Mianyang (Sichuan Mental Health Center), Mianyang 621054;
3. Department of Respiratory and Critical Care Medicine,Sichuan Science City Hospital, Mianyang 621054;
4. Department of Respiratory and Critical Care Medicine, Zhongjiang County People's Hospital, Deyang 618199, China

Received:2022-08-16 Revised:2022-12-27 Online:2023-08-05 Published:2023-07-26
Contact: ^*1721684460@qq.com

Abstract

Abstract: Chronic obstructive pulmonary disease (COPD) is a chronic and progressive respiratory disease. Transcription factor T-bet is involved in the inflammatory response and lung function changes of COPD, which is expected to become a new target for the prevention and treatment of COPD. It might provide a new idea for the targeted research of COPD.

Key words: T-bet, Th1 cell, Th2 cell, Th17 cell, chronic obstructive pulmonary disease

CLC Number:

R563

CHEN Yuting, HUANG Ling, XIA Junjie, QIU Yu, YI Ke, WANG Jincheng. Research progress on the role of transcription factor T-bet in the pathogenesis of chronic obstructive pulmonary disease[J]. Basic & Clinical Medicine, 2023, 43(8): 1322-1325.

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Research progress on the role of transcription factor T-bet in the pathogenesis of chronic obstructive pulmonary disease

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