Research progress on the role of bilirubin in inflammatory bowel disease

doi:10.16352/j.issn.1001-6325.2022.12.1925

Abstract

Abstract: The role of bilirubin in inflammatory bowel disease is not only functioned as an antioxidant and anti-inflammatory factor, but also functioned in immune regulation, anti-platelet aggregation, and as inhibition factor of digestive protease and remodeling of microbiota. Serum bilirubin level is correlated with disease activity and severity, so is a potential serum marker of inflammatory bowel disease in terms of supporting clinical diagnosis and treatment of inflammatory bowel disease.

Key words: bilirubin, inflammatory bowel disease, Crohn disease, ulcerative colitis

CLC Number:

R574.6

SHI Li, YUAN Hao, LIU Min, ZHENG Ya, WANG Yu-ping, GUO Qing-hong. Research progress on the role of bilirubin in inflammatory bowel disease[J]. Basic & Clinical Medicine, 2022, 42(12): 1925-1929.

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