Research progress on roxadustat treatment for renal anemia

doi:10.16352/j.issn.1001-6325.2022.09.1449

Abstract

Abstract: Renal anemia is an independent risk factor for progression of chronic kidney disease (CKD).Roxadustat, a novel medicine for renal anemia, utilizes the body's native response to hypoxia for activating the hypoxia-induced signaling pathway, regulating endogenous erythropoietin(EPO) production and improving iron metabolism, so effectively corrects hemoglobin level and comprehensively regulates erythropoiesis.

Key words: roxadustat, renal anemia, prolyl hydroxylase inhibitor, hypoxia-inducible factor, chronic kidney disease

CLC Number:

HU Bao-li, HU Bin. Research progress on roxadustat treatment for renal anemia[J]. Basic & Clinical Medicine, 2022, 42(9): 1449-1453.

References 20

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