Application of single-cell RNA sequencing technologies in aortic dilatation diseases

doi:10.16352/j.issn.1001-6325.2022.07.1139

Abstract

Abstract: Aortic dilation disease, represented by aortic dissection and aortic aneurysm, is the most dangerous disease in vascular surgery. The pathogenesis of this disease is not very clear. Single-cell RNA sequencing (scRNA-seq) technology can study cell heterogeneity and identify new cell states and populations at the single cell level, which provides a new tool for studying the occurrence and development mechanism of aortic disease.

Key words: aortic disease, single-cell RNA sequencing, single-cell transcriptome sequencing, high throughput RNA sequencing

CLC Number:

ZHENG Kai, REN Hua-liang, ZHANG Wang-de, LI Chun-min. Application of single-cell RNA sequencing technologies in aortic dilatation diseases[J]. Basic & Clinical Medicine, 2022, 42(7): 1139-1143.

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