[1] Orkin SH, Zon LI. Hematopoiesis: an evolving paradigm for stem cell biology[J]. Cell, 2008, 132: 631-6447. [2] Palis J, Robertson S, Kennedy M, et al. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse[J]. Development, 1999, 126: 5073-5084. [3] Tober J, Koniski A, McGrath KE, et al. The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis[J]. Blood, 2007, 109: 1433-1441. [4] Yoder MC. Inducing definitive hematopoiesis in a dish[J]. Nat Biotechnol, 2014, 32: 539-541. [5] North TE, de Bruijn MF, Stacy T, et al. Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo[J]. Immunity, 2002, 16: 661-672. [6] O'Rahilly R, Muller F. Developmental stages in human embryos: revised and new measurements[J]. Cells Tissues Organs, 2010, 192: 73-84. [7] Palis J. Primitive and definitive erythropoiesis in mammals[J]. Front Physiol, 2014, 5: 1-9. [8] Ivanovs A, Rybtsov S, Ng ES, et al. Human haematopoietic stem cell development: from the embryo to the dish[J]. Development, 2017, 144: 2323-2337. [9] Dzierzak E, Bigas A. Blood development: hematopoietic stem cell dependence and independence[J]. Cell Stem Cell, 2018, 22: 639-651. [10] Tavian M, Coulombel L, Luton D, et al. Aorta-associated CD34+ hematopoietic cells in the early human embryo[J]. Blood, 1996, 87: 67-72. [11] Tusi BK, Wolock SL, Weinreb C, et al. Population snapshots predict early haematopoietic and erythroid hierarchies[J]. Nature, 2018, 555: 54-60. [12] Nandakumar SK, Ulirsch J, Sankaran VG. Advances in understanding erythropoiesis: evolving perspectives[J]. Br J Haematol, 2016, 173: 206-218. [13] Bian Z, Gong Y, Huang T, et al. Deciphering human macrophage development at single-cell resolution[J]. Nature, 2020, 582: 571-576. [14] Grün D, van Oudenaarden A. Design and analysis of single-cell sequencing experiments[J]. Cell, 2015, 163: 799-810. [15] Freytag S, Tian L, Lönnstedt I, et al. Comparison of clustering tools in R for medium-sized 10x genomics single-cell RNA-sequencing data[J]. F1000Res, 2018, 7: 1297-1326. [16] Li J, Hale J, Bhagia P, et al. Isolation and transcriptome analyses of human erythroid progenitors: BFU-E and CFU-E[J]. Blood, 2014, 124: 3636-3645. [17] Ivanovs A, Rybtsov S, Anderson RA, et al. Identification of the niche and phenotype of the first human hematopoietic stem cells[J]. Stem Cell Reports, 2014, 2: 449-456. [18] Tavian M, Hallais MF, Péault B. Emergence of intraembryonic hematopoietic precursors in the pre-liver human embryo[J]. Development, 1999, 126: 793-803. [19] Fagerholm SC, MacPherson M, James MJ, et al. The CD11b-integrin (ITGAM) and systemic lupus erythematosus[J]. Lupus, 2013, 22: 657-663. [20] Kunishima S, Kashiwagi H, Otsu M, et al. Heterozygous ITGA2B R995W mutation inducing constitutive activation of the αIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia[J]. Blood, 2011, 117: 5479-5484. [21] Qiu X, Hill A, Packer J, et al. Single-cell mRNA quantification and differential analysis with Census[J]. Nat Methods, 2017, 14: 309-315. |