Progress in the study of the epigenetic regulation of cardiac hypertrophy

doi:10.16352/j.issn.1001-6325.2022.03.011

Abstract

Abstract: Myocardial hypertrophy is an independent risk factor for various serious cardiovascular diseases.Epigenetic mechanisms such as DNA methylation, histone modification, and RNA methylation are involved in the pathogenesis and development of cardiac hypertrophy.To understanding the role of epigenetic regulation on cardiac hypertrophy contributes to to development of an effective protocol and provide scientific basis for the prevention and early treatment of cardiac hypertrophy.

Key words: myocardial hypertrophy, epigenetics, noncoding RNA, DNA methylation, histone modification

CLC Number:

ZHENG Jing-jing, BU Ning, ZHAO Zhao, ZHANG Jia-jing, YU Hui, ZHAO Yu-hang. Progress in the study of the epigenetic regulation of cardiac hypertrophy[J]. Basic & Clinical Medicine, 2022, 42(3): 520-524.

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