Basic & Clinical Medicine ›› 2021, Vol. 41 ›› Issue (12): 1843-1847.

• Mini Reviews • Previous Articles     Next Articles

COVID-19 and hyponatremia

LIANG Si-yu1,2, CHEN Shi1*, PAN Hui1,3, JIAJUE Rui-zhi1, ZHU Hui-juan1   

  1. 1. Department of Endocrinology, Endocrine Key Laboratory of National Health Commission, Peking Union Medical College Hospital;2. Eight-year Program of Clinical Medicine;3. Department of Medical Affairs, Peking Union Medical College Hospital,CAMS & PUMC, Beijing 100730, China
  • Received:2021-05-12 Revised:2021-10-09 Published:2021-12-03
  • Contact: *cs0083@126.com

Abstract: The worldwide spread of coronavirus disease 2019 (COVID-19) has caused a heavy burden on the public health of all countries. As the specific antiviral treatment is not available, it is necessary to monitor various clinical indicators, and minimize the risk factors related to poor outcomes in the management of COVID-19. COVID-19 is often presented with hyponatremia which is frequently associated with prolonged hospitalization, increased rate of intensive care unit transfer, higher risk of severe pneumonia and mortality. Hyponatremia is an important index for early identification of patients with poor prognosis. COVID-19 related hyponatremia is mainly caused by inappropriate antidiuretic hormone secretion syndrome and hypovolemia. If hyponatremia can be diagnosed and corrected in time, the poor clinical outcomes related to hyponatremia can be prevented.

Key words: coronavirus disease 2019, hyponatremia, syndrome of inappropriate antidiuresis hormone

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