Biological characteristics and clinical application of leucocyte-and platelet-rich fibrin

Abstract

Abstract: Autologous blood-derived products get more attention as a special kind of biological products. Leucocyte-and platelet-rich fibrin (L-PRF) is the most classic second-generation platelet concentrates of autologous blood-derived products. It has more advantages than the first-generation products like platelet-rich plasma (PRP), because of the more stable fibrin network, higher concentration of cytokines and growth factors, and higher biological effects. Besides, L-PRF is easier to obtain and safer for the body. Now it has been widely used in department of stomatology, orthopedics and plastic surgery. L-PRF has the potential to serve as an ideal material for recovery and construction of soft tissues and bony defect in oncology surgery.

Key words: L-PRF, PRP, tissue repair and reconstruction, reconstruction of external ear canal

CLC Number:

Q813

SUN Hui-ying, ZHU Chong-yuan, FENG Guo-dong, GAO Zhi-qiang. Biological characteristics and clinical application of leucocyte-and platelet-rich fibrin[J]. Basic & Clinical Medicine, 2020, 40(12): 1706-1710.

References

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