Abstract: Objective To explore the methods and experience of anesthesia related management in perioperative neurosurgery patients complicated with hemophilia. Methods The clinical data of patients with hemophilia undergoing neurosurgery were collected. Results Two patients underwent neurosurgery were diagnosed as hemophilia properatively. Multidisciplinary consultation was conducted. Coagulation factor Ⅷ was perioperatively infused. Conclusions Hemophilia is a serious hereditary hemorrhagic disease. Perioperative multidisciplinary intervention, monitoring of coagulation function, timely supplementation of coagulation factors and fine anesthesia management are important for perioperative safety of patients.

Key words: hemophilia, perioperative anesthesia management, neurosurgery