Basic & Clinical Medicine ›› 2020, Vol. 40 ›› Issue (3): 395-398.

• Mini Reviews • Previous Articles     Next Articles

Research progress on the role of calcium sensing receptor in atherosclerosis

SHANG Yu-jia, LI Yu-xia, SONG Jia-xin, LI Hong-xia*   

  1. Department of Pathophysiology,School of Basic Medicine,Harbin Medical University,Harbin 150086,China
  • Received:2019-04-30 Revised:2019-09-27 Online:2020-03-05 Published:2020-03-02
  • Contact: *lihongxia_396@163.com

Abstract: Calcium sensing receptor (CaSR) is a member of the G protein-coupled receptor C family.It is widely expressed in different tissue cells in the body and functions in various pathophysiological processes of the body. CaSR can participate in the development of atherosclerosis by regulating vascular endothelial cell injury,inflammatory response,proliferation and migration of vascular smooth muscle cells and vascular calcification.

Key words: calcium sensing receptor, atherosclerosis, vascular smooth muscle cells

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