Abstract: Thyroid associated ophthalmopathy (TAO) is a familiar disease in orbit, ranking top among the orbital diseases with highest incidence. Traditional treatment includes the use of corticosteroids, radiotherapy and surgical treatment. In recent years, relative researches about selenium, biological immunosuppressive agents have been increased and showed great potential in the treatment of TAO.

Key words: Thyroid associated ophthalmopathy, Selenium supplement therapy, Biological agents, Orbital decompression