Abstract: PBL teaching method (problem-based leaning) has been widely carried out in pathology teaching, but it still have limitations in the implementation, and integrated medicine concepts could improve the effect of PBL teaching to a great extent. In this paper, by analyzing the necessity of integrated medicine concepts in the pathological PBL teaching, some principles are put forward to optimizing PBL teaching, including the principle of integration and the networking, unpack and topology, and perfecting the "typical case selection and the shortage of PBL mechanism". Finally, the paper indicates that deep understanding of complementary relationship between integrated medicine and PBL could help to establish medical scenario, which is easier to understand, operate and grasp, thus to promote the pathological teaching reform.

Key words: integrated medcine, PBL, pathology