Abstract: As a new laboratory test for evaluation of endogenous pain inhibition, conditioned pain modulation (CPM) deficiency means dysfunction of endogenous pain inhibitory systems and higher incidence of chronic pain. Age, psychological factors and physical activity all seem to influence the individual CPM effect. A standard CPM testing way has an important role in comparison between different researches.

Key words: Conditioned pain modulation (CPM), diffuse noxious inhibitory controls (DNIC), chronic pain, personal factors, testing methods