Basic & Clinical Medicine ›› 2015, Vol. 35 ›› Issue (11): 1567-1571.

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Progress in the detection and targeted therapy of epidermal growth factor receptor variant III in ovarian cancer

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  • Received:2015-04-16 Revised:2015-06-29 Online:2015-11-05 Published:2015-11-03

Abstract: The epidermal growth factor receptor variant III (EGFRvIII) also known as the most common mutant form of EGFR is a tumor-specific mutation, hasn’t yet been detected in normal tissues. It is regarded as a tumor-specific gene and offers a new way for targeted therapy of ovarian cancer.

Key words: epidermal growth factor receptor, epidermal growth factor receptor variant III, ovarian cancer, targeted treatment

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