Abstract: microRNA (miRNA) are a class of small non-coding RNA molecules have expression mediated gene transcription regulatory functions, long non-coding RNA (lncRNA) is untranslated transcripts with the number of bases greater than 200 nucleotides, through a variety of mechanisms including gene imprinting, chromatin remodeling, cell cycle regulation exerts its biological function.It has been found there exist the interaction relationship between miRNA and lncRNA,and plays an important role for tumorigenesis,tumor development and treatment.

Key words: Key words: Tumor, microRNA, lncRNA, Interaction regulation