Abstract: Tumor markers as a non-invasive examination method not only play very important role in the diagnosis and classification of cancer, also has an important role to monitor disease recurrence and determine the efficacy of treatment.At present, the existing methods do not achieve the desired detection sensitivity and specificity. With the development of high-throughput technology, many molecular markers for bladder cancer have been discovered , such as DNA / RNA, proteins, and metabolites or the combination of them provide a more accurate methods for bladder cancer detection.

Key words: Keywords: bladder cancer, Molecular markers