Abstract: Objective To discuss the correlation between anthropometric indexes and insulin resistance in T2DM patients after gastric bypass. Methods To retrospective analysis of 42 T2DM patients after laparoscopic gastric bypass, we assessed the anthropometric indexes by body fat instrument and detect islet function indicators by OGTT test before and 6 months post gastric bypass. Results After 6 months of gastric bypass, the remission rate of diabetes was 78%（32/41）. The fasting plasma glucose,body weight,body mass index,waist circumstance,hip circumstance,waist to hip ratio,body fat, insulin resistance index,insulin affective index and insulin sensitive index were significantly decreased compared with before(P<0.05). Preoperative insulin resistance index was significantly correlated with trunk fat (P <0.05). Postoperative insulin resistance was positive correlated with weight, body mass index, waist circumference, hip circumference and body fat（P<0.05）. Insulin affect index was negative correlated with body weight, body mass index, hip, hip drop value and body fat (P<0.05). Conclusion After laparoscopic gastric bypass, the changes of trunk fat content was the biggest in T2DM patients; the changes of body fat especially in abdomen in T2DM patients are associated with insulin resistance improvement.

Key words: Gastric bypass, T2DM, anthropometric indexes, insulin resistance