Abstract: Objective To evaluate the relative risk factors and impact of adjuvant treatment on the disease recurrence of early-stage cervical adenocarcinoma. Methods One hundred and eighteen FIGO Ia2-IIa2 patients diagnosed with cervical adenocarcinoma were treated at Peking Union Medical College Hospital (PUMCH) from Nov, 1995 to Feb, 2012. The demographic, treatment and survival information were retrospectively reviewed. Follow-up and survival data was also collected. Data were analyzed using Cox proportional hazards regression. Results The mean age of the patients was 41 years (19-74years). 102 of 118 patients (86.4%) were given radical hysterectomy and/or bilateral salpingo-oophorectomy (BSO) and/or lymphadenectomy during the primary treatment. With the mean follow-up time 29.8 months (2-132months), 19 patients developed disease recurrence and 7 patients died of the disease. In the univariate analysis, old age (p=0.008), late-stage disease (p=0.008), large tumor (p=0.006) , pelvic nodal metastasis (p=0.001) and deep stromal invasion（p=0.016）were related to tumor recurrence. While in the multivariate analysis, pelvic nodal metastasis was the only independent risk factor. For the patient with high-risk factors, chemoradiation after radical hysterectomy could prolong the disease free survival but have no statistical significance (P = 0.201). Conclusion Adenocarcinoma is a kind of poor survival cervical cancer in early-stage patients. Pelvic nodal metastasis is the independent risk factor. Adjuvant chemoradiation after radical hysterectomy may prolong the disease free survival in patients with high-risk factors.