基础医学与临床 ›› 2010, Vol. 30 ›› Issue (1): 103-106.

• 短篇综述 • 上一篇    

Wnt /β-catenin信号传导通路与早期胚胎心脏发育的关系

陈筠 孙莉   

  1. 桂林医学院 桂林医学院
  • 收稿日期:2009-03-30 修回日期:2009-06-01 出版日期:2010-01-05 发布日期:2010-01-05
  • 通讯作者: 孙莉

The relation between cardiac development and wnt /β-catenin signal transduction in early embryo

Jun CHEN, Li SUN   

  1. Guilin Medical University
  • Received:2009-03-30 Revised:2009-06-01 Online:2010-01-05 Published:2010-01-05
  • Contact: Li SUN

摘要: Wnt /β-catenin 信号传导通路是调控细胞增殖、运动、分化的关键途径,在胚胎发育方面起重要作用。研究者发现wnt信号通路是早期刺激心脏发生的重要调节因素,与早期胚胎的心脏形态发生有密切联系。本文就目前wnt信号通路与早期胚胎心脏发育的研究进展进行综述。

关键词: wnt/β-catenin信号, 胚胎早期, 心脏

Abstract: The wnt/β-catenin signal transduction pathway is an access regulating cell proliferation, movement, differentiation and plays crucial roles in embryo development. The researchers have found that Wnt pathway is an important regulation factor in the early stimulation of the cardiogenesis and contacts closely the several key events during cardiac morphogenesis. The article reviews the recent studies about the relation between cardiac development and Wnt pathway in early embryo.

Key words: wnt/β-catenin signal transduction, early of embryo, heart