EBUS-TBNB在纵隔肿大淋巴结诊断中的应用及优势

doi:10.16352/j.issn.1001-6325.2025.05.0671

基础医学与临床 ›› 2025, Vol. 45 ›› Issue (5): 671-674.doi: 10.16352/j.issn.1001-6325.2025.05.0671

EBUS-TBNB在纵隔肿大淋巴结诊断中的应用及优势

骆玉兔, 黄磊, 刘俊, 田胤纯, 刘云, 潘家华^*

泰州市第二人民医院呼吸与危重症医学科,江苏泰州 225500

收稿日期:2025-01-02 修回日期:2025-03-18 出版日期:2025-05-05 发布日期:2025-04-23
通讯作者: ^* jy_panjh@163.com

Application and advantage of EBUS-TBNB in the diagnosis of enlarged mediastinal lymph nodes

LUO Yutu, HUANG Lei, LIU Jun, TIAN Yinchun, LIU Yun, PAN Jiahua^*

Department of Respiratory and Critical Care Medicine, Taizhou Second People′s Hospital, Taizhou 225500, China

Received:2025-01-02 Revised:2025-03-18 Online:2025-05-05 Published:2025-04-23
Contact: ^* jy_panjh@163.com

摘要/Abstract

摘要： 目的探讨与支气管内超声引导的针吸活检(EBUS-TBNA)相比,支气管内超声引导的淋巴结活检(EBUS-TBNB)技术在肺癌及肺外肿瘤纵隔淋巴结转移、淋巴结炎性反应、结节病等伴有纵隔肿大淋巴结疾病中的诊断优势。方法收集2023年3月至2024年7月间,泰州第二人民医院呼吸内科收治的纵隔疾病、且符合纳入标准的患者35例。全部行EBUS-TBNA和EBUS-TBNB,并进行病理检测。结果病理检测结果显示:EBUS-TBNA恶性肿瘤检出率为(14/35,40%),操作过程平均出血量为1~2 mL;与EBUS-TBNA相比,EBUS-TBNB的恶性肿瘤检出率为(23/35,66%)(P＜0.01),另外检出4例肉芽肿,平均出血量3~4 mL。结论与EBUS-TBNA相比,EBUS-TBNB恶生肿瘤的病理阳性检出率高,在良性增生性疾病诊断中更具有优势,可以进一步提高纵隔肿大淋巴结诊断的准确率和灵敏度,值得临床推广应用。

关键词: 纵隔淋巴结, 支气管超声引导, 针吸活检, 淋巴结活检

Abstract: Objective Compared with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), this study aims to explore the diagnostic advantages of endobronchial ultrasound-guided transbronchial node biopsy (EBUS-TBNB) in the diagnosis of mediastinal lymph node metastasis, lymphadenitis, sarcoidosis and other mediastinal lymph node diseases associated with mediastinal enlargement in lung cancer and extra-pulmonary tumors. Methods The detection rate of malignant tumor was(14/35, 40%) by EBUS-TBNA and average amount of bleeding during each operation was 1-2 mL; Compared with EBUS-TBNA, the detection rate of malignant tumors by EBUS-TBNB was(23/35, 66%)(P＜0.01), and 4 cases of granulomas were diagnosed, and the average amount of bleeding during each operation was 3-4 mL. Conclusions Compared with EBUS-TBNA, EBUS-TBNB has a higher detection rate for malignant tumors and has more advantages in the diagnosis of benign proliferative diseases. It can further improve the accuracy and sensitivity of diagnosing mediastinal enlarged lymph nodes so is worthy of clinical promotion and application.

Key words: mediastinal lymph nodes, endobronchial ultrasound-guided (EBUS), needle aspiration, node biopsy

中图分类号:

R563. 9

骆玉兔, 黄磊, 刘俊, 田胤纯, 刘云, 潘家华. EBUS-TBNB在纵隔肿大淋巴结诊断中的应用及优势[J]. 基础医学与临床, 2025, 45(5): 671-674.

LUO Yutu, HUANG Lei, LIU Jun, TIAN Yinchun, LIU Yun, PAN Jiahua. Application and advantage of EBUS-TBNB in the diagnosis of enlarged mediastinal lymph nodes[J]. Basic & Clinical Medicine, 2025, 45(5): 671-674.

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EBUS-TBNB在纵隔肿大淋巴结诊断中的应用及优势

Application and advantage of EBUS-TBNB in the diagnosis of enlarged mediastinal lymph nodes

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