脑电图、肌电图及临床症状学在双侧强直发作局灶性癫痫定侧中的价值评估

doi:10.16352/j.issn.1001-6325.2023.08.1289

基础医学与临床 ›› 2023, Vol. 43 ›› Issue (8): 1289-1293.doi: 10.16352/j.issn.1001-6325.2023.08.1289

脑电图、肌电图及临床症状学在双侧强直发作局灶性癫痫定侧中的价值评估

孙利, 李放, 王晓梅, 刘兴洲^*

首都医科大学附属复兴医院神经内科,北京 100038

收稿日期:2023-05-21 修回日期:2023-06-25 出版日期:2023-08-05 发布日期:2023-07-26
通讯作者: ^*liusinclair@yahoo.com.cn
基金资助:
西城区优秀人才——拔尖团队项目(202153)

Evaluation of EEG, EMG and clinical semiology in the lateral location of bilateral extremities tonic seizures of focal epilepsy

SUN Li, LI Fang, WANG Xiaomei, LIU Xingzhou^*

Department of Neurology, Fuxing Hospital, Capital Medical University, Beijing 100038, China

Received:2023-05-21 Revised:2023-06-25 Online:2023-08-05 Published:2023-07-26
Contact: ^*liusinclair@yahoo.com.cn

摘要/Abstract

摘要： 目的比较电-临床特征对双侧强直发作的局灶性癫痫的定侧价值。方法根据手术及随访结果,回顾性观察26例局灶性癫痫患者92次双侧肢体强直发作,对其发作期脑电图、同步表面肌电图及临床症状学进行分析。结果 59.8%(55/92)的脑电图可明确提示侧别;伴随侧向征象有64.1%(59/92)正确定侧;81.5%(75/92)的强直关节运动可正确定侧;表面肌电图正确定侧率为85.9%(79/92),后两者较前两者的阳性率高,具有统计学意义。结论强直关节运动和表面肌电图具有良好的侧向性定位价值,两者对癫痫术前评估具有指导意义。

关键词: 双侧强直发作, 电-临床症状学, 定位, 定侧

Abstract: Objective To evaluate the lateralizing value of electrical and clinical semiology in patients with bilateral extremities tonic seizure (BETS). Methods Ninety-two times of BETS were retrospectively observed from 26 patients with focal epilepsy, based on the surgery and follow-up results. The ictal electroencephalography(EEG),synchronous surface electromyography(EMG) and clinical symptoms were collected. Results The EEGs were correctly lateralizing in 59.8%(55/92)seizures.The accompanying lateral signs were correctly lateralized in 64.1%(59/92)seizures. The tonic joint movement lateralization was correct in 81.5%(75/92)seizures. The surface EMGs were 85.9%(79/92)correctly lateralized. The positivity rate of the latter two was higher than that of the first two, which was statistically significant. Conclusions Both the tonic joint movement and surface EMG have better lateralization value and guiding significance for preoperative evaluation of patients with epilepsy.

Key words: bilateral extremities tonic seizures(BETS), electrical-clinical semiology, positioning, lateralization

中图分类号:

R742.1

孙利, 李放, 王晓梅, 刘兴洲. 脑电图、肌电图及临床症状学在双侧强直发作局灶性癫痫定侧中的价值评估[J]. 基础医学与临床, 2023, 43(8): 1289-1293.

SUN Li, LI Fang, WANG Xiaomei, LIU Xingzhou. Evaluation of EEG, EMG and clinical semiology in the lateral location of bilateral extremities tonic seizures of focal epilepsy[J]. Basic & Clinical Medicine, 2023, 43(8): 1289-1293.

参考文献 14

[1]	Seneviratne U,Christie H,D'Souza W,et al.Semiologic differences between bilateral tonic-clonic seizures of focal onset and generalized onset[J].Epilepsy Behav,2022,134:108837.doi: 10.1016/j.yebeh.2022.108837.
[2]	Foldvary N,Klem G,Hammel J,et al. The localizing value of ictal EEG in focal epilepsy[J]. Neurology, 2001,57:2022-2028.
[3]	Luders H,Acharya J,Baumgartner C,et al. Semiological seizure classification[J]. Epilepsia, 1998, 39: 1006-1013.
[4]	Elwan S, Alexopoulos A, Silveira DC,et al. Lateralizing and localizing value of seizure semiology:comparison with scalp EEG, MRI and PET in patients successfully treated with respective epilepsy surgery[J]. Seizure,2018,61:203-208.
[5]	Turek G, Skjei K. Seizure semiology, localization, and the 2017 ILAE seizure classification[J]. Epilepsy Behav,2022,126:108455.doi: 10.1016/j.yebeh.2021.108455.
[6]	Katyal R, Kubota T, Georgia MD, et al. Bilateral tonic seizures vs. bilateral tonic events in critically ill patients: differences in semiology[J].Seizure,2023,109:5-11.
[7]	Mcgonigal A. Semiology and epileptic networks[J].Neurosurg Clin N Am,2020,31:373-385.
[8]	Morkavuk G, Isik K, Leventoglu A. A different look on the importance of lateralization and localization of figure 4 symptoms in epilepsy[J]. Egypt J Neurol Psychiatry Neurosurg, 2022,58:36.doi:10.1186/s41983-022-00467-9.
[9]	Wong CH, Mohamed A,Larcos G, et al. Brain activation patterns of versive, hypermotor, and bilateral asymmetric tonic seizures[J].Epilepsia,2010,51:2131-2139.
[10]	Kikuchi T,Matsumoto R,Mikuni N, et al. Asymmetric bilateral effect of the supplementary motor area proper in the human motor system[J]. Clin Neurophysiol,2012,123:324-334.
[11]	Xu YW, Lin P, Yao PS,et al. Structure and function of corticospinal projection originating from supplementary motor area[J]. Neuroradiology,2021,63:1283-1292.
[12]	Cai GL,Wang J,Mei X,et al. Electroclinical semiology of the bilateral asymmetric tonic seizures observed in patients with supplementary sensorimotor area epilepsy confirmed by pre- and post-operative MRI[J].J Xray Sci Technol,2017,25:247-259.
[13]	Punyawai P, Usui N, Kondo A, et al. Semiological differences of focal onset bilateral motor (convulsive) seizure between mesial temporal lobe epilepsy and neocortical epilepsy[J]. Epilepsy Res,2021,170:106553.doi: 10.1016/j.eplepsyres.2021.106553.
[14]	Elwan S, Alexopoulos A,Silveira DC,et al. Lateralizing and localizing value of seizure semiology: comparison with scalp EEG, MRI and PET in patients successfully treated with respective epilepsy surgery[J]. Seizure, 2018,61:203-208.

脑电图、肌电图及临床症状学在双侧强直发作局灶性癫痫定侧中的价值评估

Evaluation of EEG, EMG and clinical semiology in the lateral location of bilateral extremities tonic seizures of focal epilepsy

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献 14

相关文章 8

编辑推荐

Metrics

本文评价

[1]	赫佳音, 杨嘉宾, 陈仲扬, 马艳妮, 余佳. 烯醇化酶1通过影响mRNA定位调节人胚胎干细胞自我更新能力[J]. 基础医学与临床, 2023, 43(6): 867-874.
[2]	苏越, 梁琳慧, 何祥火. 长链非编码RNA亚细胞定位和功能的研究进展[J]. 基础医学与临床, 2023, 43(10): 1580-1584.
[3]	张璐, 李智, 隋昊, 史立晖. 超声引导下导丝定位切除术治疗触诊阴性乳腺病灶的价值[J]. 基础医学与临床, 2020, 40(6): 822-824.
[4]	周凡琦, 冯文新, 谭普文, 马艳妮, 王栋, 余佳. 人胚胎干细胞RNA的细胞质和细胞核内的定位[J]. 基础医学与临床, 2020, 40(6): 765-770.
[5]	赵婧谢雪梅陈玉蓉. 肿瘤抑制因子PTEN亚细胞定位与缺血-缺氧性脑损伤[J]. 基础医学与临床, 2016, 36(12): 1718-1722.
[6]	周家名陈莉王桂兰秦婧吴圆圆. 沉默EMS1/cortactin基因对肝癌HepG2细胞迁移、侵袭和细胞周期的影响[J]. 基础医学与临床, 2016, 36(12): 1664-1669.
[7]	张晓燕刘佳王菁丁洁管又飞. 固醇调节元件结合蛋白-1在小鼠肾脏的表达定位[J]. 基础医学与临床, 2013, 33(12): 1621-1623.
[8]	宁丽峰王慧萍李铁桑建利李佳慧. 内源性PS1在活体HEK293和HeLa细胞膜上的定位[J]. 基础医学与临床, 2012, 32(12): 1400-1405.