基础医学与临床 ›› 2014, Vol. 34 ›› Issue (2): 266-269.

• 短篇综述 • 上一篇    下一篇

内皮祖细胞与肢体缺血疾病的研究现状

孙艺玮1,姜维良2   

  1. 1. 哈尔滨医科大学附属第二医院
    2. 哈尔滨医科大学附属第二医院血管外科
  • 收稿日期:2013-04-02 修回日期:2013-05-23 出版日期:2014-02-05 发布日期:2014-01-13
  • 通讯作者: 姜维良 E-mail:wljiang6666@sohu.com

The current research status of Endothelial progenitor cells and limb ischemia diseases

  1. 1. Department of general surgery,second affiliated Hospital of Harbin Medical University,Harbin
    2.
  • Received:2013-04-02 Revised:2013-05-23 Online:2014-02-05 Published:2014-01-13

摘要: 肢体缺血性疾病已成为发达国家及许多发展中国家的主要疾病之一,而干细胞移植是治疗肢体缺血性疾病备受关注的新方法。内皮祖细胞( EPCs)可分化为内皮细胞,参与新生血管生成。研究证实, 体内移植EPCs可以促进缺血后组织内的血管新生, 为缺血性疾病治疗提供了新策略。

关键词: 内皮祖细胞, 血管新生, 缺血性疾病

Abstract: Limb ischemic disease has become one of the major diseases of developed countries as well as many developing countries, and stem cell transplantation is a new method for treatment in limb ischemic diseases ,it has attracted much attention. Endothelial progenitor cells (EPCs) can differentiate into endothelial cells involved in angiogenesis. Many studies have confirmed that the transplanted EPCs in the body can promote angiogenesis in ischemic tissue.

Key words: endothelial progenitor cells, angiogenesis, ischemic disease

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