振动反应成像技术在弥漫性肺实质病的应用初探

基础医学与临床 ›› 2012, Vol. 32 ›› Issue (6): 702-706.

振动反应成像技术在弥漫性肺实质病的应用初探

金贝贝,许文兵

中国医学科学院北京协和医学院北京协和医院呼吸内科

收稿日期:2012-03-28 修回日期:2012-04-25 出版日期:2012-06-05 发布日期:2012-05-25
通讯作者: 许文兵 E-mail:xuwenbingly@yahoo.com.cn

Exploration of vibration response imaging in evaluating diffuse parenchymal lung disease

Received:2012-03-28 Revised:2012-04-25 Online:2012-06-05 Published:2012-05-25

摘要/Abstract

摘要： 摘要:目的初步探讨振动反应成像（VRI）检查在弥漫性肺实质疾病中的图像特点，进而总结其临床应用价值方法选择2010年7月至2011年2月期间在北京协和医院呼吸科住院的胸部影像学表现为双下肺索条、网格、蜂窝影的弥漫性肺实质疾病（DPLD）的病人35例做为试验组，同期招募健康成年人33例作为对照组。VRI设备采用VRIxp系统，按照研究步骤（问诊、查体、VRI检查等）采集两组人员临床及VRI信息。采用非参数检验以及t检验等统计学方法，对DPLD组及正常对照组的VRI图像特点，包括振动能量曲线、图像动态发展、MEF面积、左肺QLD值、干湿罗音监测等方面进行分析。结果 DPLD组振动曲线评分2(1~3)，动态图像发展评分3(2~4)，健康对照组振动曲线评分0(0~1)，动态图像发展评分0(0~1)，两组比较有显著差异（P<0.05）,其中DPLD组观察动态图像发展，可见吸气相能量团显著向中下移心而双上肺能量缺失。DPLD组MEF面积(71.13±4.94)千像素,左肺QLD值（54.31±11.34）%；健康对照组MEF面积(71.61±3.42)千像素,左肺QLD值（56.70±6.02）%，两组比较无显著差异（P>0.05）；DPLD组VRI监测的干湿罗音与听诊符合度为89%。结论影像学以双下肺索条、网格、蜂窝样改变为主的DPLD患者，VRI图像有自己的特点，且与正常人存在差异，希望今后VRI检查可用于早期探测间质性肺疾病的发生。

关键词: 弥漫性肺实质疾病, 振动反应成像, 呼吸音

Abstract: Abstract:Objective To explore the value of vibration response imaging (VRI) system in evaluating the patients with diffuse parenchymal lung disease (DPLD).Methods 35 DPLD patients that their CT show reticulation and honeycombing in the base of the lung and 33 healthy volunteers were enrolled,Clinical examination and VRI test were performed.The parameters of VRI included vibration energy graph grades, dynamic image grades,areas of Maximal energy frame(MEF), quantitative lung data(QLD) and crack .The statistical analysis was performed using 2 Independent Samples Tests and Independent-Samples T test.Results The VRI parameters of the DPLD group were as follows,ie.graph grades of 2(1~3),dynamic image grades of 3(2~4),MEF areas of (71.13±4.94)kilo-pixels,QLD of （54.31±11.34）%(left).The VRI parameters of the control group were as follows,ie. graph grades of 0(0~1),dynamic image grades of 0(0~1),MEF areas of (71.61±3.42)kilo-pixels,QLD of（56.70±6.02）% (left) .There were significant differences in graph grades and dynamic image grades(P<0.05) ,otherwise MEF areas and QLD were not.Energy move down during inspiration in DPLD patients.Crack detectation was consistent with auscultation in 89% subjects.Conclusion VRI results of DPLD patients that their CT show reticulation and honeycombing in the base of the lung have its characters.there was a statistical difference between the VRI results of DPLD patients and healthy subjects.VRI will be helpful in diagnosing DPLD during its early stage.

Key words: Diffuse parenchymal lung disease, Vibration response imaging, Respiratory sounds

中图分类号:

R445.9

金贝贝许文兵. 振动反应成像技术在弥漫性肺实质病的应用初探[J]. 基础医学与临床, 2012, 32(6): 702-706.