Abstract: Objective To explore the safety and effect of angioplasty with Apollo stent for symptomatic intracranial arterial stenosis. Methods Twenty-two symptomatic intracranial arterial stenosis patients (24 arteries) underwent Apollo stent placement. The follow-up period was 3-28 months (average 14 months). Successful rate, perioperative complications, pre- and post-operative National Institute of Health Stroke Scale (NIHSS), in-sent restenosis (ISR), stroke recurrence and case-fatality rate were asessed. Results Procedural and clinical success was achieved in 22 (91.67% ) target vessels. The degree of stenosis was reduced from the baseline of (73.23 ± 9.59)% to (4.12 ± 9.17)% after stenting (t = 3.325, P = 0.005). No perioperative complications occurred. Neural function was improved (NIHSS score: postoperation, 0.59 ± 1.35 vs. preoperation, 0.59 ± 1.74; t = 2.718, P = 0.015). No in?stent restenosis was seen by CT angiography (CTA). No patients had stroke recurrence or died. Conclusion Angioplasty and stenting with Apollo stent for treating symptomatic intracranial arterial stenosis is safe and effective.

Key words: Brain ischemia, Cerebral arterial diseases, Angioplasty, Stents

摘要： 目的 探讨Apollo支架治疗症状性颅内动脉狭窄的安全性及临床疗效。方法 采用Apollo支架植入治疗22 例（24 支）症状性颅内动脉狭窄患者，随访3 ~ 28 个月，平均14 个月，分别观察技术成功率和围手术期并发症、手术前后神经功能缺损程度、随访期间支架内再狭窄发生情况，以及脑卒中复发率和病死率。结果 Apollo支架植入治疗症状性颅内动脉狭窄的技术成功率为91.67%（22/24），平均狭窄率由手术前（73.23 ± 9.59）%降至手术后（4.12 ± 9.17）%（t = 3.325，P = 0.005）。围手术期未发生手术相关并发症，手术后神经功能缺损程度显著改善［美国国立卫生研究院卒中量表（NIHSS）评分：（0.59 ± 1.35）比（0.59 ± 1.74）；t = 2.718，P = 0.015］。临床随访无脑卒中复发或死亡病例，CTA 随访无支架内再狭窄。结论 Apollo支架植入治疗症状性颅内动脉狭窄可行且安全有效。

关键词: 脑缺血, 脑动脉疾病, 血管成形术, 支架