我院老年住院患者潜在不适当用药情况的分析

doi:10.11669/cpj.2022.04.012

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摘要目的回顾性分析我院老年住院患者潜在不适当用药的情况,以期降低老年患者的用药风险。方法选取2019年1~12月北京医院老年住院患者(年龄≥65岁)为研究对象,以Beers标准(2019版)、STOPP标准(2014版)以及中国老年人PIM判断标准(2017版)为依据,再结合我院的实际用药情况,分析评价我院老年住院患者潜在不适当用药(PIM)的发生情况。结果有15 935(70.77%)人次患者存在PIM,共计48 227例次。药物相关PIM中频度最高的是质子泵抑制剂(PPI,20.57%),其次是氯吡格雷(17.78%);疾病状态下PIM频度最高的是高血压患者服用非甾体抗炎药(NSAIDs,47.17%),其次是骨质疏松患者服用糖皮质激素(GC,11.71%);最常见的药物相互作用相关的PIM是GC和NSAIDs合用(35.85%);其次是≥2种NSAIDs合用(26.88%)。结论我院老年住院患者PIM比例较高,应采取相应的干预措施,降低老年人用药风险,保障用药安全。

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	罗太敏
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	倪倩
	尹美慧
	谭琳
	谭玲

关键词 ：潜在不适当用药, Beers标准, STOPP标准, 中国老年人潜在不适当用药判断标准

Abstract：OBJECTIVE Toretrospectively analyze the situation of potential inappropriate drug use (PIM) in elderly inpatients in our hospital. METHODS The elderly inpatients (aged over 65 years) in Beijing hospital from January to December in 2019wereretrospectively analyzed. PIM was evaluated according to beers standard (version 2019), STOPP standard(version 2014) and PIM judgment standard for Chinese elderly(version 2017).Combined with the medication situation of our hospital, the PIM situation of elderly inpatients in our hospital was analyzed. RESULTS The results showed that there were 15 935(70.77%) patients with PIM, a total of 48 227 cases.The most frequentdrug-related PIM was PPI (20.57%), followed by clopidogrel (17.78%).The frequency of PIM was highest in hypertension patients taking NSAIDs (47.17%), followed by osteoporosis patients taking glucocorticoids (11.71%);The most common drug interaction related PIM was the combination of glucocorticoids and NSAIDs (35.85%), followed by the combination of ≥ 2 NSAIDs (26.88%). CONCLUSION The proportion of PIM is high, and corresponding intervention measures should be taken to reduce the risk of medication and ensure the safety of medication.

Key words： PIM Beers criteria STOPP criteria PIM criteria for the elderly in China

收稿日期: 2021-02-22

PACS:

R969.3

基金资助:国家重点研发计划资助(2020YFC2009001)

通讯作者: * 谭玲,女,主任药师研究方向:医院药学

作者简介: 罗太敏,女,硕士,主管药师研究方向:医院药学

引用本文:

罗太敏, 李婷, 倪倩, 尹美慧, 谭琳, 谭玲. 我院老年住院患者潜在不适当用药情况的分析[J]. 中国药学杂志, 2022, 57(4): 315-320. LUO Tai-min, LI Ting, NI Qian, YIN Mei-hui, TAN Lin, TAN Ling. Analysis of Potential Inappropriate Medication in Elderly Inpatients in Our Hospital. Chinese Pharmaceutical Journal, 2022, 57(4): 315-320.

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http://journal11.magtechjournal.com/Jwk_zgyxzz/CN/10.11669/cpj.2022.04.012 或 http://journal11.magtechjournal.com/Jwk_zgyxzz/CN/Y2022/V57/I4/315

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